Lors du tout premier Symposium scientifique du Centre intersectoriel d'analyse des perturbateurs endocriniens (CIAPE), Julie Robitaille, étudiante au docotorat au Centre Eau Terre Environnement, a reçu le Prix CIAPE 2022 pour ses contributions exceptionnelles dans la recherche sur les perturbateurs endocriniens.
Le 11 avril prochain, de 12h-14h, Julie Robitaille donnera une conférence en ligne à propos de ses travaux de recherche.
Pour vous inscrire et en savoir plus : https://www.ciape-iceda.ca/conferences-laureats/
Toward monitoring endocrine disrupting chemicals in freshwater using bioassays: From developing a strategy in Quebec to building OECD recommendations
Endocrine disrupting chemicals (EDCs) are a type of chemicals which can interact with the hormonal system and generate adverse effects. The release of EDCs in aquatic environment can have important impact on wildlife by affecting reproduction, growth, and behaviour. Despite those known impacts, EDCs are still hardly regulated in freshwater around the world. Moreover, there is a need to move from traditional chemical monitoring to effect-based monitoring which uses bioanalytical tools or bioassays. Through this presentation, the use of bioassay for monitoring EDCs will be explored first by focusing on the strategy being developed for wastewater in the province of Quebec, Canada. In this strategy, wastewater sample would be evaluated for EDCs using a two-Tier bioassay-based approach. The first Tier of testing would be completely in vitro and composed of the transactivation assay for the receptor of estrogen (ER) and androgen (AR). The second Tier would be in vivo with the fish shortterm reproduction assay in Pimephales promelas, which would only be use if a confirmation of effect is required. Results from current validation study using municipal wastewater will be presented. In the second part of the presentation, the process of developing policy recommendations for EDCs in freshwater for OECD countries will be discussed. Through the evaluation of country case studies, a conceptual framework is currently being created to guide regulators and other stakeholders in the development of a monitoring strategy for EDCs based on their need. The framework aims to inform on available choice for the design of a monitoring strategy, the monitoring methods, the ways to palliate uncertainties and the possible mitigation action. This works also highlights the need for international collaboration on various topics such as the standardization of methods and the development of bioassays for other endpoints